A new study looks at the evaluation and management of carpal tunnel syndrome (CTS). The Journal of the American Academy of Orthopaedic Surgeons reports approximately 500,000 surgical procedures on CTS are performed each year in the United States. The economic impact due to CTS is estimated to exceed $2 billion annually.

Brian J. Hartigan, MD, clinical assistant professor of orthopaedic surgery at Northwestern University Feinberg School of Medicine in Chicago, co-authored this study—which was published in the September 2007 issue—looking at CTS evaluation and management.

"Most patients with CTS present to their orthopaedic surgeon with numbness, tingling and weakness in their hands and fingers. Occasionally, pain can occur and go up the arm or into the shoulder. Theses symptoms are caused by median nerve compression," Hartigan says.

Most cases of CTS do not have an identifiable cause. Women are more commonly afflicted than men and incidence increases with age. Other conditions associated with carpal tunnel syndrome may include:

• Wrist Trauma
• Obesity
• Hypothyroidism
  

Additionally, rheumatoid arthritis and renal (kidney) failure may lead to an increase in pressure within the carpal tunnel; drug toxicity, diabetes and alcoholism may have direct injurious effects on the median nerve. CTS also occurs in 20% to 45% of all pregnancies, however it typically disappears after childbirth.

"Some people believe that work activities that involve overuse of the wrist and hand, repetitive impact on the palm and tools that vibrate can cause CTS," Hartigan says. "Extremes of wrist flexion and extension have been shown (experimentally) to elevate pressure within the carpal tunnel. However, the relationship between repetitive work activity and CTS has never been objectively demonstrated."

Medical history and physical examination are key in the diagnosis of CTS. An orthopaedic surgeon will evaluate for other conditions that can mimic CTS including neck problems, thoracic outlet syndrome, and other nerve compression syndromes.

If conservative treatments fail, endoscopic or open carpal tunnel release surgery may be necessary. Open carpal tunnel release is the most common method of surgical treatment. Although endoscopic surgery has been found to shorten recovery time, studies have demonstrated no substantial differences in outcomes between endoscopic and open surgery.

Complications of surgery are infrequent but can occur. Recurrent carpal tunnel syndrome develops in 7 to 20 percent of surgical cases and revision surgery is less successful than primary carpal tunnel release surgery.

"Although our understanding of CTS has come a long way, additional basic science and clinical outcome studies are needed to solve the many uncertainties and controversies that still exist," Haritgan says.

[Source: American Academy of Orthopaedic Surgeons]